Unfortunately there is no benefit to not taking estrogen. I see women weekly and sometimes daily whose lives have been destroyed by lack of estrogen. Women who never take estrogen develop just as much breast cancer as women who take estrogen. Not taking estrogen delays the diagnosis for 1 to 2 years. This makes the prognosis worse. Women should start estrogen at menopause and continue it lifelong. Without estrogen women age fast. Women not on estrogen eventually begin to shrink, and then shrink progressively and continually. This does not need to happen. Within 2 years of starting estrogen women in their 60s, 70s, 80s and 90s stop losing height and do not shrink for at least the next 5 years.

Goals

Understand the data and trends of the WHI.
Understand the available data and how the WHI relates
to this.
Understand why women need Postmenopausal hormone and estrogen
therapy.

Article

Risks and Benefits of Estrogen plus Progestin in Healthy
Postmenopausal Women JAMA, July 17, 2002 – Vol 288:
321-333 Copyrighted 2002, American Medical Association

Studied 16,608 women average age 63 randomized to oral
horse estrogen(OHE) 0.625mg and medroxyprogesterone acetate(MPA)
over average time of 5.2 years.

An article published July 17, 2002 in JAMA by authors from the National Cancer Institute concludes that women, who use estrogen replacement therapy, particularly for 10 or more years, were at a significantly increased risk of ovarian cancer. The relative risk in that study was increased, but the absolute risk was incredibly small. The relative risk for taking estrogen alone was increased by 1.6, but the absolute risk was increased from 4.4 cases per 10,000 women-years to 6.5 cases per 10,000 women-years. This is an absolute increase of 2.1 cases per 10,000 women-years, equivalent to the one year risk of driving of 1:5000. After 10 years the relative risk was reported as 1.8, “a significant increased,” but the absolute risk was increased from 4.4 to 6.9 cases per 10,000 women, an increase of 2.5 cases per 10,000 women, less risk than driving for two years.

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Blane Crandall, MD, LLC Naples OBGYN About Blane Crandall, MD, LLC (Naples OBGYN) Dr. Crandall is a Board Certified Obstetrician and Gynecologist located in Naples Florida. Additionally, he has been trained and has worked as a Family Practice physician. As such, he cares for all your medical needs, not just Obstetrics and Gynecology. He specializes […]

Naples Gynecologist and Obstetrician Blane Crandall, MD likes to see all patients on an appointment basis and requests that patients call well in advance so that we can reserve time especially for you. If you are unable to keep an appointment, we would appreciate at least 24 hours notice. This courtesy will allow us to schedule […]

BIO Staff Appointment Date: 3/22/1989 Specialty: Obstetrician/Gynecologist Board Certification: Obstetrician/Gynecologist Professional Education: Emory University School of Medicine 1970 – 74 Internship: Silas B. Hays Army Hospital 7/74 – 6/75 Residency: Family Practice – Silas B. Hays Army Hospital (7/75 – 6/77). OB/GYN Madigan Army Medical Center (7/84 – 6/87) Blane Crandall, MD, LLC Naples OBGYN […]